Neurology Medicine

Posts Tagged ‘Physical Examination’

This disease and Lambert Eaton syndrome, presented as common feature the presence of autoantibodies that play a primary pathogenic role in the neuromuscular junction. Recent studies also suggest the presence of autoimmune reactions at the neuromuscular junction in amyotrophic lateral sclerosis.

Patients with myasthenia gravis have a weakness and easy fatigability in skeletal muscle. The weakness may be absent at rest but increases with the run of the day and especially with sustained or repeated exercise.
The weakness is detectable on physical examination especially in the extra ocular muscles, bulbar innervated muscles and limbs. Read the rest of this entry »

As in most autoimmune diseases of unknown etiology, diagnosis is established on the basis of “criteria” which, according to the number that are present, will generate the EM categories of possible, probable and definite.
Schumacher criteria for diagnosing MS are:

1. “Two separate symptoms of central nervous system.
2. “Two separate outbreaks (between the debut and the second outbreak at least one month).
3. “Symptoms that should involve the white matter.
4. -Age of onset of 20-40 years.
5. Objectified-neurological deficit on physical examination.
6. “No other satisfactory medical explanation for this clinical picture.
The key criterion is in the first two points: two lesions separated in time and space. Read the rest of this entry »