Posts Tagged ‘Behcet’s Disease’
Behcet’s Disease: DIAGNOSIS AND TREATMENT
Behcet’s disease diagonosis is based on long-term clinical observation. The differential diagnosis includes recurrent oral aphthosis, Reiter’s syndrome, Crohn’s disease, ulcerative colitis, multiple sclerosis, SLE and other brain tumors among
Because the cause of the disease is unknown, treatment is done according to individual symptoms and the time of onset. The drugs are to reduce inflammation or to attempt to regulate the immune system. Some of the drugs used are: Read the rest of this entry »
Behcet’s Disease: ETIOLOGY AND PATHOGENESIS
The etiology and pathogenesis of this syndrome remain unclear. It is considered an autoimmune disease as the common denominator in many patients is the vasculitis. Found antibodies to oral mucous membranes and immune complexes in 50% of cases. The antigen HLA-B85 (B51 and B52) is 3-4 times more frequent among patients than among controls.
Behçet’s disease is rare, chronic evolution and the ability to produce inflammation at the level of the blood vessels of the body, so it is considered a systemic vasculitis. Although initially considered a disease of the Mediterranean countries and Japan, is now known that the disease is spread throughout the world. The description of cases increasing in Asian countries means that many authors relate their distribution to remote trade routes and give the name of disease in the Silk Road. Read the rest of this entry »
Behcet’s Disease: DESCRIPTION
In 1937, Dr. Hulusi Behçet, Turkish doctor described a syndrome characterized by a triad of signs: aphthous stomatitis, genital ulcers and uveitis (presence of inflammatory cells in the anterior chamber of the eye).
The recurrent oral thrush (100% of cases) are painful and have a variable size and appearance alone healing in 1-3 weeks without scarring.
The genital sores (60-80%) are located on the glans penis and scrotum in males and the vulva, vagina and cervix in women, being painful and slow to heal in the male, much less troublesome in women. Uveitis, bilateral almost always present in 60-70% of patients. Sometimes associated choroiditis, vitreous hemorrhage, optic neuritis, retinal and other vascular disorders that can lead to blindness if left untreated the disease. Read the rest of this entry »